Why Phycox EQ Granules?

• Horses Love the Taste
• Phycox®-EQ Palatability is GUARANTEED
• Sweet Apple and Molasses Flavor

Phycox®-EQ Directions for Use

Average Horse....2 scoops daily
Over 1200 lb....3 scoops daily

Maintenance Administration:
Average Horse....1 scoop daily
Over 1200 lb....1½ scoops daily

Available Package Sizes

2.88 kg    (90 scoops)

Joint Support Formula

For healthy synovial maintenance as well as bone and muscle support.

• Glucosamine HCl
• Methylsulfonylmethane (MSM)
• Creatine Monohydrate
• Alpha Linolenic Acid (Flaxseed Oil sourced)
• Turmeric
• Omega-3 Fatty Acids
• Boron
• Selenium
• Alpha Tocopheryl Acetate (Vitamin E)

Also contains a proprietary blend of Citrus Bioflavonoids, Calcium Phosphate, Manganese Sulfate, Ascorbic Acid (Vitamin C), Zinc Sulfate, Alpha Lipoic Acid and Grape Seed Extract.

Dynamic Antioxidant

Has powerful free radical scavenging properties. It can help enhance the body’s defense against degradative effects that cause cellular damage and play a role in a host of degenerative conditions in horses.

 

Arthritis is a painful condition

There are two major forms of arthritis. Rheumatoid arthritis is a common form of arthritis which involves inflammation of the joints, swelling, pain, and loss of function. The primary symptom of rheumatoid arthritis is inflammation of the synovial membrane. The membrane thickens and synovial fluid accumulates. The resulting pressure causes pain and tenderness.

The most common form of arthritis, osteoarthritis, is a degenerative joint disease that is far more common than rheumatoid arthritis. It is characterized by the deterioration of articular cartilage and the formation of new bone in the subchondral areas and at the margins of the joint.The cartilage slowly degenerates and as the bone ends become exposed small bumps of new osseous tissue are deposited on them. These bumpsdecrease the space in the bone cavity and restrict joint movement.

Cyclooxygenase Enzymes

Two isoforms of cyclooxygenase exist

• Cyclooxygenase-l (COX-1)
• Cyclooxygenase-2 (COX-2)

Both catalyze the reaction that converts arachidonic acid into a class of hormones known as eicosinoids, which include prostaglandins, prostacyclins, and thromboxanes.

COX-1 is expressed in all mammalian tissues, and serves a variety of homeostatic physiologic functions. It is responsible for the production of protective prostaglandins in the kidney and the stomach, as well as the functional thromboxane of platelets.

COX-2 is not normally found in most tissues, and is expressed under conditions of tissue damage. COX-2 leads to the biosynthesis of prostaglandins, triggering pain and inflammatory responses.

COX Selective Inhibitors

A form of non-steroidal anti-inflammatory drug (NSAID) that directly targets COX-2, an enzyme responsible for inflammation and pain. Selectivity for COX-2 reduces the risk of peptic ulceration when taken over extended periods of time.

Phycocyanin

It has been discovered that a blue-green algae extract and, more particularly, phycocyanin functions as a COX-2 inhibitor that is effective in treating arthritis and other inflammatory conditions in animals. The use of phycocyanin is now patented and effective in reducing inflammation in animals through its ability to selectively inhibit the COX-2 enzyme.^{1, 2, 3}

Clinical Study

• 41 horses with moderate to severe arthritis and inflammatory conditions showed statistically significant, owner-perceived improvements in:
  • mobility
  • alertness
  • activity level
  • ability to change position from lying down to standing
  • pain level
  • general activity
• 80% of the horses experienced some benefit within thirty days of Phycox^® use
• 93% responded after four months ²

PHYCOX^®-EQ GRANULES