Indications

Recommended for use as an aid in the control of Canine Infectious Tracheobronchitis (Kennel Cough) caused by the organism represented.

Bordetella Bronchiseptica Bacterin, Cellular Antigen Extract

Shake well. Aseptically administer 1 mL subcutaneously. Healthy dogs should receive 2 doses administered 2-4 weeks apart. Annual revaccination with a single dose is recommended.
The effect of persisting B. bronchiseptica maternal antibody on the immune response in puppies to the bacterin has not been determined. Puppies from bitches immune to the organism usually have low antibody titers that are dissipated by 4-6 weeks of age. Although kennel cough is considered a disease of complex etiology, it can be reproduced by challenge with B. bronchiseptica alone. A close association and/or confinement of dogs facilitates spread of the disease syndrome. Antibiotic therapy has been shown to be generally unsuccessful in reducing or eliminating B. bronchiseptica in dogs.

• Store at 2°-7°C (35° to 45°F)
• Prolonged exposure to higher temperatures may adversely affect potency.
• Do not freeze.
• Use entire contents when first opened.
• Sterilized syringes and needles should be used to administer this vaccine.
• Transient local irritation at the site of injection, though rare, may occur subsequent to use of this product.
• As with many vaccines, anaphylaxis may occur after use. 

Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy

Discussion

The effect of persisting B. bronchiseptica maternal antibody on the immune response in puppies to this bacterin has not been determined. Puppies from bitches immune to the organism usually have low antibody titers that are dissipated by 4-6 weeks of age. Although kennel cough is considered a disease of complex etiology it can be reproduced by challenge with B. bronchiseptica alone. A close association and/or confinement of dogs facilitates spread of the disease syndrome. Antibiotic therapy has been shown to be generally unsuccessful in reducing or eliminating B. bronchiseptica in dogs.



by Pfizer/Zoetis

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Zoetis

Bordetella Bronchiseptica Bacterin

Cellular Antigen Extract

For use in dogs only

Bronchicine CAe is a nonadjuvanted antigenic extract prepared from the cells of Bordetella bronchiseptica recommended for use as an aid in the control of canine infectious tracheobronchitis (kennel cough) caused by the organism represented.

The effect of persisting B. bronchiseptica maternal antibody on the immune response in puppies to this bacterin has not been determined. Puppies from bitches immune to the organism usually have low antibody titers that are dissipated by 4-6 weeks of age. Although kennel cough is considered a disease of complex etiology, it can be reproduced by challenge with B. bronchiseptica alone. A close association and/or confinement of dogs facilitates spread of the disease syndrome. Antibiotic therapy has been shown to be generally unsuccessful in reducing or eliminating B. bronchiseptica infection in dogs.

Directions: Shake well. Aseptically administer 1 mL subcutaneously to healthy dogs at least 8 weeks of age. For initial vaccination, a second dose is required 2-4 weeks later. This product should be administered by subcutaneous injection only. Annual revaccination with a single 1 mL dose is recommended.

Precautions: Store at 2°-7°C. Do not freeze. Use entire contents when first opened. Care should be taken to avoid microbial contamination of the product. In case of anaphylactoid reactions, epinephrine should be administered immediately. Transient local irritation at the site of injection, though rare, may occur subsequent to use of this product.

Technical inquiries should be directed to Zoetis Inc. Veterinary Services, (888) 963-8471 (USA), (800) 461-0917 (Canada).

U.S. Veterinary License No. 190

Zoetis Inc., Kalamazoo, MI 49007, USA

50 1-dose (1-mL) vials of bacterin	13845700
5 10-dose (10-mL) vials of bacterin	13845201

CPN: 3690232.4